(Ch3)  Conformational analysis continued:
Cycloalkanes....Cycloalkanes aren't planar, they are "puckered" (3.4)
Cyclohexane : chair, boat and other conformers, axial, equatorial positions and substituent preferences. (3.7-3.12)
Return to elimination reactions to cover the more advanced aspects.... i.e. E2 selectivity in cyclic systems.

Types of isomers.
As time allows, examples of application of reactions in problems e.g. synthesis, reactions of etc.

Lecture templates: See course documents folder in Blackboard. Problem set

1,2-Elimination reactions : Alkene stability. E1 and E2 mechanisms. Regioselectivity (Zaitsev's rule) and stereoselectivity.
Dehydrohalogenations of alkyl halides. Dehydration of alcohols.

(Ch3)  Conformational analysis of alkanes and cycloalkanes : terminology, ethane, butane etc. (3.1-3.3)
Cycloalkanes....Cycloalkanes aren't planar, they are "puckered" (3.4)
Cyclohexane : chair, boat and other conformers, axial, equatorial positions and substituent preferences. (3.7-3.12)

Lecture templates: See course documents folder in Blackboard. Problem set

Nucleophiles and nucleophilicity, comparing nucleophilicity to basicity, leaving groups.
Reaction mechanisms: SN2 and SN1 reactions, carbocation intermediates
Substitution reactions of alkyl halides including Williamson ether synthesis and use of acetylides and enolates.
Substitution reactions of alcohols including using tosylates and thionyl chloride.
Solvent effects in SN reactions

Lecture templates: See course documents folder in Blackboard. Problem set

Solving spectroscopy problesm. Other issues in H NMR : "accidental equivalence", complex coupling patterns

Overview of Nucleophilic Substitution reactions (Ch 4 and Ch 8)
Nucleophiles and nucleophilicity, comparing nucleophilicity to basicity, leaving groups.
Reaction mechanisms: SN2 and SN1 reactions, carbocation intermediates

Lecture templates: See course documents folder in Blackboard. Problem set

Ch 13 : Continue spectroscopy :

Nuclear magnetic resonance (NMR), 
Characteristic chemical shifts, "levels" of information in H-NMR, integration, coupling patterns, coupling constants and the n+1 rule,

C-NMR : comparison with H-nmr, typical 13C chemical shifts, interpretting 13C spectra

Th F are the F10 reading days : there are no classes on those days.

Lecture templates: See course documents folder in Blackboard. Problem set

Ch 13 : Continue spectroscopy :
Infra-red spectroscopy : principles,  important absorptions, interpretting IR spectra
Nuclear magnetic resonance (NMR),  basic principles,  chemical shift, shielding, magnetic anisotropy

Lecture templates: See course documents folder in Blackboard.

Radical halogenation of alkanes (4.15-4.19)
Review oxidation and reduction of organic molecules. (2.19)

Ch 13 : Spectroscopy : Background.  
Overview of the spectroscopic methods (MS, IR, H-NMR, 13C-NMR) : What do each of them tell you ?
How to solve spectroscopy problems.
Mass spectrometry : basis and terminology isotope patterns.

Lecture templates: See course documents folder in Blackboard. Problem set

Complete acidity and basicity (1.12-1.17) ..... rationalising acidity and basicity by looking at factors that affect these properties at the molecular level. Application of principles.

Review Hydrocarbons (2.11-2.18): Types of hydrocarbon (2.1) saturation and unsaturation, alkanes and cycloalkanes isomers, physical properties related to structure (intermolecular forces), thermodynamic stability

Lecture templates: See course documents folder in Blackboard. Problem set

No classes on Monday (Thanksgiving)

Acidity and basicity (1.12-1.17) review definitions, Ka and pKa, rationalising acidity and basicity by looking at factors that affect these properties at the molecular level. 

Lecture templates: See course documents folder in Blackboard.

Complete resonance by seeing it "in action"

Curly arrows : (1.11) make them talk to you !    Drawing mechanisms = "mechanistic story questions". Formal charges (1.7)
Acidity and basicity (1.12-1.17) review definitions, Ka and pKa, rationalising acidity and basicity by looking at factors that affect these properties at the molecular level. 

Lecture templates: See course documents folder in Blackboard. Problem set

Bonding in organic systems : (2.1, 2.5-2.7)  hybridisation for hydrocarbons (2.20-21) then other heteroatom systems (2.22) (Flash animation for hybridisation).
Orbitals in bonding of alkenes and alkynes. (2.20-21) Comparing bonding and bond properties in alkanes, alkenes and alkynes.
Resonance (1.8, very, very IMPORTANT !) - implications of structure, recognising and ranking resonance contributors, examples of "resonance in action"

Lecture templates: See course documents folder in Blackboard.

From Ch 1 : Review of ionic and covalent bonding with examples from organic chemistry.  Lewis structures
Structure and function : polar covalent bonds : acidity, pKa, bond properties : molecular geometries.
In Ch 2 : Bonding (2.2-2.4) : What happens at the molecular level when atoms interact ?  Electron density animation of 2 interacting H atoms -> H₂  Combining waves - in and out of phase. How do covalent bonds form and molecular orbitals ? Bonding and anti-bonding orbitals. Why no He₂ ? 

Lecture templates: See course documents folder in Blackboard.

Introduction to Organic Chemistry. What to expect, what to do, what not to do etc.  How to work for success. Our expectations. Overview of course components, using CPS, podcasts etc.
Chemistry 351 concept map. The language of organic chemistry, definitions of key terms.  Electronegativity.

Lecture templates: See course documents folder in Blackboard.