|Chapter 2: Alkanes|
|Qu : The structure of EPOTHILONE A, a compound with
anticancer activity similar to Taxol is shown to the right.
(a) What is the hybridisation of the following C atoms
in Epothilone A ?
(b) Arrange the following bonds in Epothilone A in order of decreasing length:
(c) What type of bonding MOLECULAR orbitals are involved in the bonds between C3-C4 and C17-C18 ?C14-C15 C15-C17 C17-C18
(d) What are the oxidation states of the following
C atoms in Epothilone A ?
(e) Identify any C-C σ bonds in Epithilone A that are not between a pair of sp3
hybridised C atoms.
|© Dr. Ian Hunt, Department of Chemistry|