Preparation of Organocopper
- The most useful organocopper
reagents are lithium dialkylcuprates, R2CuLi.
- Lithium dialkylcuprates are formed
by the reaction of 2 equivalents of an organolithium with a copper (I) halide.
- Typical solvents are normally
anhydrous diethyl ether or tetrahydrofuran.
- The alkyl group is usually primary.
Secondary and tertiary are prone to decomposition.
- Halide reactivity : I > Br >
can be alkyl, vinyl or aryl.
||© Dr. Ian Hunt, Department of Chemistry, University