||Chapter 14: Organometallic
Preparation of Acetylenic
Reaction type: acid-base
- In Ch9 we saw that terminal acetylenes
can be deprotonated using sodium amide, NaNH2 (review
- Acetylenic Grignard reagents,
RC≡CMgX, can also be prepared.
- Rather than starting from the
acetylenic halides, they are prepared by an acid-base reaction of the terminal
acetylene with a second Grignard reagent.
- Acetylenic Grignards react in
a similar fashion to other Grignard reagents.
||© Dr. Ian Hunt, Department of Chemistry, University