Part 9: SYNTHESIS

The schemes below give possible syntheses of the targets. There are of course other variations. The first part for each compound gives a "retro-synthesis", the "plan" and then the required forward synthesis with reagents is given. Red arrows try to show carbon-carbon bond forming reactions, blue arrows are functional group manipulations. The blue text rationalise the retrosynthetic analysis and information about important reactions are given in green.


diene synthesis


cyclopentane carboxylic acid synthesis


tertiary diol synthesis


trisubs. aromatic


diphenylethene synthesis


diamine synthesis


Common general errors: (1) poor choice of reagents and / or conditions (2) incorrect starting materials (3) ignoring regio and / or stereoselectivity issues.


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