||Chapter 19: Carboxylic
Reaction type: Substitution
- Reagents most commonly : Br2
and either PCl3, PBr3 or red phosphorous in catalytic amounts.
- Carboxylic acids can be halogenated
at the C adjacent to the carboxyl group.
- This reaction depends on the
enol type character of carbonyl compounds.
- The product of the reaction,
an a-bromocarboxylic acid can be converted via
substitution reactions to a-hydroxy-
or a-amino carboxylic acids.
|© Dr. Ian Hunt, Department of Chemistry, University