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Chapter 23: Aryl Halides |  |
Aryl Grignards
- Aryl Grignards are formed by the reaction of aryl halides (X= Cl, Br or I) with magnesium metal.
- Typical solvents are normally anhydrous diethyl ether or tetrahydrofuran.
- Halide reactivity : I > Br > Cl
- Aryl Grignards undergo the sample types of reactions as alkyl Grignard reagents (review)
- Organolithium reagents can also be made.
- Aryl Grignard reactions allow for the introduction of C substituents other than via Friedel-Crafts alkylation or acylation reactions.
Related reactions
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© Dr. Ian Hunt, Department of Chemistry, University of Calgary | |