Chapter 25: Carbohydrates
Acylation of Carbohydrates
Reaction type: Nucleophilic Acyl Substitution
The -OH groups in carbohydrates react
readily with acylating agents such as acid
halides or acid anhydrides to give
Most commonly, the esters used will be an ethanoate (also commonly known
as an acetate and represented as "Ac")
|| This representation shows the same product as that in the scheme
at the top of the page.
These reactions are often used in carbohydrate chemistry since the products
act as protecting groups for the
reactive -OH functional group.
||© Dr. Ian Hunt, Department of Chemistry, University