CHEM353 Weekly Bulletin
|
CHEM353 WEEKLY
BULLETIN |
CHEM353W26 Organic
Chemistry II
last
modified :
The best preparation for CHEM353 is a solid grasp of all that went before, especially the core concepts from Chem 351: you will need to know those materials.
CHEM353W26 wk 7 Mar 2-6 2026 :
As a reminder, CHEM353W26 MT runs in week 8 on WED MAR 11 2026, 19:00-21:00 (locations TBA in D2L).
ANY student who has a class conflict with this out of class activity, as per the course outline and UofC guidelines, needed to have reported the conflict 14 days prior to the scheduled MT date (Wed Feb 25th 2026).
If you have not done so, :( , you should do so now, and make sure to send a copy of your schedule to Dr Hunt (irhunt@ucalgary.ca) so that an alternate time slot on Mar 11th can be arranged (i.e. not a deferred MT, which is something different). The final deadline for requests is Mon Mar 2rd, 16:30.
Watch for a D2L News post about 353W26 MT coverage (it is expected to be all 353 content up to and including the chemistry of conjugated systems (week 7) which is consistent with the last few years of CHEM353 MT examinations).
LABORATORY
- Remember that your plastics report (single PDF file, one time submission), is due to the appropriate D2L Dropbox by the start of your scheduled laboratory session (week of Mar 2-6 2026).
- This week in the laboratory, you will be performing a fractional distillation, a technique used to separate a mixture of miscible liquids.
- The distillation report (one PDF file, one time submission), is due to the appropriate D2L Dropbox by the start of your next scheduled laboratory session (Mar 16-20 2026).
- As preparation, you are required to:
- submit a pre-lab summary (pdf to appropriate D2L Dropbox)
- review the CHEM353 student manual (section 7) for more details on the pre-lab summary content and expectations (section 7, p8)
- complete the pre-lab quiz (in Moodle) by 30mins before the start of your scheduled laboratory session
- complete the pre-lab quiz that will be available from 06:00 the day before your scheduled laboratory session
- Bring a copy of the experimental procedure & techniques documents to the laboratory session
- Safety ! Be dressed appropriately, have your safety glasses and laboratory safety coat to wear while working in the laboratory (mandatory).
- No food or drink is allowed at any time in a laboratory environment.
CAL TUTORIALS
- This week, write CAL353 assignment 3, the chemistry of alkenes and alkynes 2 (properties, spectroscopy, preparations, reactivity, reactions (halogenations, halohydration, ozonolysis, dihydroxylation, cyclopropanation, epoxidation and their reactions).
- Remember that your are required to write your assignment during your scheduled CAL time.
- During times when students are writing assignments, only students working on assignments are allowed in the CAL room SA 204.
- Official picture ID is required (place it on the top of the PC tower while you are writing your assignment).
- CAL assignments are to be written under exam conditions (see course information sheet or Moodle policy, check with the CAL TA before starting work if you have any doubts).
- We provide the scrap paper (which must be handed in at the end : recycling box at the front).
- Periodic tables and spectroscopy tables are provided within Moodle. Model kits and simple calculators are alowed. No other resources (paper or electronic) are allowed.
- Attending tutorials each week to talk to the organic chem TA is very strongly recommended.
- Questions on tutorial related issues should be directed to the CHEM353W26 course coordinator, Dr Hunt.
- The weekly tutorial sessions occur, in-person, in SA204.
- In terms of tutorials, if you miss or will miss your tutorial in a:
- non-assignment week either (a) make up the missed time remotely on your own or (b) drop in to a 353 tutorial at another time (access is first come, first served for non-registered students).
- assignment week then complete this form based on the information here (to report absence and request excused absence)
L01 LECTURE topics week by week (the etext links are the potentially valuable details here). The yellow box represents the current week and the table will grow each week to provide a record of where we have been.
Wk 7
(Mar 2-6) |
etext Ch 10
Types of dienes : conjugated, isolated and cumulated.
Conjugated dienes, kinetic
and thermodynamic control, 1,2- vs 1,4- (or direct vs conjugate) additions e.g. additions
of hydrogen halides (HX)
Conjugated dienes : direct (1,2)- and conjugate (1,4)-additions of halogens
(X2).
The Diels-Alder
reaction : terminology, selectivity etc.
How
to analyse and design an organic synthesis
Corresponds to content modules 11B-D, 12 (D2L content folder will be updated as we progress) |
Wk 6
(Feb 23-27) |
Ozonolysis
of alkenes and alkynes considering both oxidative and reductive work-ups.
Synthesis
of 1,2-diols via oxidation of alkenes with KMnO4 or OsO4
Cyclopropanation
reactions of alkenes
Study tool : make a table about the reactions (note no audio, just a table to complete from notes "review")
etext Ch 10 Conjugated systems. Terminology - conjugation, resonance, allylic systems : reactivity
Corresponds to L01 content modules 08C, D 09-11A (D2L content folder) |
| (Feb 16-20) |
SEMESTER BREAK (no classes) |
Wk 5
(Feb 9-13) |
Hydration
of alkynes to ketones (via enol tautomerism) contd.
Hydroboration
/ oxidation of alkynes.Halogenations
of alkenes
Halogenations
of alkenes and alkynes.
Halohydration of alkenes (reactions with X2 / H2O and HOX).
An introduction to epoxides. Preparations : epoxidation of alkenes using peracids and synthesis
from halohydrins via intramolecular Williamson type ether synthesis.
An introduction to the reactions
of epoxides with various nucleophiles (strong vs weak), regio- and
stereochemistry.
Corresponds to L01 content modules 06D, 07, 08A-C (D2L content folder) |
Wk 4
(Feb 2-6) |
Hydrohalogenation : addition of HX to alkynes to give vinyl halides and alkyl dihalides.
Radical
addition of HBr to alkynes.
Hydration of alkenes : addition using H3O+ (i.e. aqueous acid) to give alcohols
Hydroboration
/ oxidation of alkenes
Oxymercuration
/ demercuration reactions of alkenes
Hydration
of alkynes to ketones (via enol tautomerism)
Corresponds to L01 content modules 05B, 06A-D, 07 (D2L content folder will be updated as we progress) |
Wk 3
(Jan 26-30) |
Introduction
to addition reactions. Transformations, regiochemistry,
and stereochemistry.
Catalytic hydrogenations of alkenes and alkynes.
Hydrohalogenation : addition of HX (HCl, HBr, HI) to alkenes to give alkyl halides (inc. radical addition of HBr)
Markovnikov's
Rule - origins of the empirical observation (i.e. intermediate stability).
Hydrohalogenation : addition of HX to alkynes to give vinyl halides and alkyl dihalides.
These topics are covered in content modules 04, 05A & B (D2L content folder) |
Wk 2
(Jan 19-23) |
etext Ch 7: stereochmistry review, optical activity, polarimetry, specific rotation. Fischer projections.
etext Ch 6 Addition
reactions of alkenes and etext Ch 9 addition reactions of alkynes
Start with a quick review of alkenes and alkynes: alkene nomenclature, alkyne nomenclature, structure, phys. properties, preparations of alkenes and alkynes.
Alkene and alkyne reactivities: what is their role in reactions ? Introduction
to addition reactions. Transformations, regiochemistry,
and stereochemistry.
Corresponds to video content modules 02A, B & C (Optical Activity 1-3) + 03A & B (D2L content folder) |
Wk 1
(Jan 12-16) |
Introduction to Organic Chemistry
II. What to expect, what to do, what not to do etc.
A little review of a few issues : key concepts from 351 Organic
chemistry concept map, the families
of reaction mechanisms, learning reactions.
etext Ch 7: Isomer types (review), Optical activity, polarimetry, specific rotation. Fischer projections.
Corresponds to video content modules 00A & B ("Intro & Prep" ), 01 (Learning Reactions), 02A (Optical Activity 1) (D2L content folder) |
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